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Common blood thinners may speed up artery calcification, study suggests

NCT ID NCT02823093

Knowledge-focused Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether vitamin K antagonists (a type of blood thinner) are linked to more calcium buildup in the aorta, the body's main artery. Researchers compared 73 patients—some on the drug for at least 6 months and some who never took it—using CT scans. The goal was to see if these medications might contribute to artery hardening.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
vitamin K antagonists (blood thinners)
What this could lead to
If it succeeds, this could clarify whether vitamin K antagonists worsen aortic calcification, guiding safer prescribing.
What could go wrong
This is a small, observational study with only 73 participants, so results may not apply broadly. It cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

73 people

The number who actually took part.

Started

Apr 2016

Finished

Mar 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

One group treated by VKA treatment for at least 6 months and one focus droup which have never been treated by VKA treatment.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients having a abdominal scanner without injection planned at CHU Amiens * group treated by VKA: VKA treatment for at least 6 months * group not treated by VKA: no antecedent of AVK treatment Exclusion Criteria: * abdominal scanner contre indication * progressive cancer * scanner planned by emergency department * patient having had acute cardiovascular accident in the last 3 months

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Conditions

The condition(s) this trial relates to.

calcinosis Vascular Calcification

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Vascular calcification

Contacts and locations

Locations

  • CHU Amiens

    Amiens, 80054, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.