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Heart bypass patients get new hope: three-drug trial aims to keep arm artery grafts open longer

NCT ID NCT04310995

First seen Apr 15, 2026 · Last updated May 24, 2026 · Updated 8 times

Summary

This study compares three oral medications (nicorandil, diltiazem, and isosorbide mononitrate) to prevent spasms in radial artery grafts used in coronary artery bypass surgery. About 150 adults who recently had this surgery will take one of the drugs for 24 weeks, with follow-up imaging and check-ups to see which drug best keeps grafts open and reduces heart events. The goal is to find the most effective anti-spasm treatment to improve long-term outcomes after bypass surgery.

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Contacts and locations

Locations

  • Ruijin Hospital Shanghai Jiaotong University School of Medicine

    Shanghai, 200025, China

Conditions

Explore the condition pages connected to this study.