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Antioxidant cocktail may shield seniors from bed rest damage

NCT ID NCT04351113

First seen May 01, 2026 · Last updated Jun 22, 2026 · Updated 6 times

Summary

This study tests whether antioxidant supplements can prevent muscle loss and blood vessel problems in older adults (ages 65-85) during five days of bed rest. Participants take either the supplements or a placebo, and researchers measure changes in blood flow and muscle function. The goal is to find a way to protect vulnerable seniors from the harmful effects of inactivity, such as during hospital stays.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • VA Medical Center

    Salt Lake City, Utah, 84148, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

antioxidant supplements (MITO-AO and PB-125)

What this could lead to

If it works, this could point toward a simple supplement strategy to protect older adults from muscle loss and blood vessel problems during hospital stays or bed rest.

What could go wrong

This is a small, early-stage study with only 82 participants, and it tests short-term bed rest in healthy older adults, not real hospital patients. The supplements may not work in real-world conditions or for everyone.

Conditions

The condition(s) this trial relates to.

muscular atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.