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Can special alloy rings keep dental implants cleaner?

NCT ID NCT05122897

Knowledge-focused Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study tests whether temporary rings made of an antimicrobial alloy, placed on dental implant abutments, can reduce bacterial biofilm compared with standard titanium alloy rings. About 33 adults with one or more titanium implants will wear these rings, which are removed and replaced at 48 hours, 2 weeks, and 3 months to measure bacterial load and composition. The goal is to see if the antimicrobial material can limit plaque and potentially lower the risk of peri-implantitis, a common cause of implant failure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Rings made of antimicrobial alloy (Pagalinor, PA) compared with titanium alloy (TAN) rings placed on dental implant abutments
What this could lead to
If the antimicrobial alloy rings reduce biofilm, they could help prevent dental plaque and peri-implantitis around implants, improving long-term implant health.
What could go wrong
This is a small early-stage study, so results may not apply broadly. The rings are temporary and only tested in healthy people without active gum disease, and the alloy's effect on mature biofilm is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 33 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2022

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed Consent signed by the subject * Presence of one or more bone level titanium implant prior to insertion of the final restoration * No systemic illness * No heavy smoking (smoking \<10 cigarettes/day) * No pregnancy * No active periodontitis (probing pocket depth ≤4 mm) * No pharmacological treatment or antibiotic therapy during or up to three months before the study Exclusion Criteria: * Systemic illness (e.g. Diabetes) * Heavy smoking (smoking \>10 cigarettes/day) * Known or suspected non-compliance, drug or alcohol abuse * Pregnancy * Active periodontitis (probing pocket depth \>4 mm) * Pharmacological treatment or antibiotic therapy during or up to three months before the study

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Conditions

The condition(s) this trial relates to.

Dental Plaque Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental plaque Oral biofilm Peri-implantitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UZB (University Center for Dental Medicine Basel)

    RECRUITING

    Basel, 4058, Switzerland

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