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UTI antibiotics may harm gut bugs, study finds

NCT ID NCT07424989

First seen Feb 24, 2026 · Last updated Jun 20, 2026 · Updated 18 times

Summary

This study looked at how antibiotics used to treat urinary tract infections (UTIs) change the bacteria in your gut. Researchers collected stool samples from 61 hospitalized adults before and after antibiotic treatment to see if resistant bacteria increased. The goal was to understand side effects of common UTI antibiotics on digestive health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU de Rouen

    Rouen, 76031, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

antibiotics (ceftriaxone, piperacillin/tazobactam, or temocillin)

What this could lead to

If successful, this could help doctors choose antibiotics that treat UTIs while minimizing harm to gut bacteria and reducing antibiotic resistance.

What could go wrong

This is a small, completed observational study, not a treatment trial. It only measures changes in gut bacteria, so it won't directly improve UTI care or prove any new therapy works.

Conditions

The condition(s) this trial relates to.

urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.