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Antibiotics for gum disease: do they really work?

NCT ID NCT06131021

First seen May 05, 2026 · Last updated May 23, 2026 · Updated 4 times

Summary

This study tested whether adding antibiotics (amoxicillin and metronidazole) to standard deep-cleaning treatment helps adults with gum disease. 236 participants from dental practices across the U.S. were randomly assigned to get either antibiotics or a placebo along with their cleaning. The main goal was to see if antibiotics improved pocket depths around teeth after 6 weeks. The results help dentists decide when to use antibiotics for gum disease.

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Contacts and locations

Locations

  • University of Alabame

    Birmingham, Alabama, 35233, United States

Conditions

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