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Shorter antibiotic course may be just as good for facial fractures

NCT ID NCT04925531

Knowledge-focused Sponsor: Methodist Health System Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving antibiotics for 3 days instead of 5 days after facial fracture surgery makes a difference in preventing infections. Researchers enrolled 143 trauma patients to compare the two durations. The goal is to find the shortest effective antibiotic course to reduce side effects and antibiotic resistance.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Antibiotics (ampicillin, cefazolin, erythromycin)
What this could lead to
If shorter antibiotic use works as well, it could reduce side effects and bacterial resistance in facial fracture patients.
What could go wrong
This is a small, completed study with 143 patients, so results may not apply to everyone. The best antibiotic duration is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

143 people

The number who actually took part.

Start date

Jul 2016

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

trauma patients who were admitted to MHS between January1st 2010 and December 31st 2015

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female patient's ≥ 18 years of age. * Blunt and penetration injury. Exclusion Criteria: * Pregnant and breast feeding women.

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Conditions

The condition(s) this trial relates to.

Accidental Injuries injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Trauma injury

Contacts and locations

Locations

  • Methodist Dallas Medical Center

    Dallas, Texas, 75203, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.