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Bone graft study: immune reactions under the microscope

NCT ID NCT07474857

Knowledge-focused Sponsor: Medical Innovation Center Wroclaw Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether bone grafts used before dental implants cause the body to make antibodies that might affect healing. Twenty healthy adults needing bone augmentation received either animal or human donor bone, and half also got laser therapy. Blood and bone samples were taken before and after surgery to measure immune markers and check how well the bone healed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Jul 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Patients requiring bone augmentation procedures prior to dental implant placement * Insufficient alveolar bone volume requiring regenerative treatment * Good general health condition * Ability and willingness to provide written informed consent Exclusion Criteria: * Systemic diseases affecting bone healing * Active oral infections or inflammatory conditions at the surgical site * Use of medications affecting bone metabolism (e.g., bisphosphonates) * Pregnancy or breastfeeding * Heavy smoking * Previous bone grafting procedures in the planned surgical site

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone loss Maxillary sinus bone loss

Contacts and locations

Locations

  • MCIW - Wroclaw Medical Innovation Center

    Wroclaw, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.