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Experimental CAR-T therapy targets tough solid tumors in small pilot trial

NCT ID NCT06556108

First seen Jan 22, 2026 · Last updated Apr 30, 2026 · Updated 12 times

Summary

This study tested a new treatment called Anti-ALPP CAR-T cells in 5 people with advanced solid tumors that had not responded to standard therapies. The treatment uses a patient's own immune cells, modified to attack a protein (ALPP) found on many cancer cells. The main goals were to check safety and see if tumors shrank.

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Contacts and locations

Locations

  • Department of Hematology, Xinqiao Hospital

    Chongqing, Chongqing Municipality, 400037, China

Conditions

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