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Remote HIIT program aims to boost fitness in ANOCA patients

NCT ID NCT07182955

Knowledge-focused Sponsor: University of Virginia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at why people with angina but no blocked arteries (ANOCA) often have poor fitness. Researchers will test whether a 4-week, remotely supervised high-intensity interval training (HIIT) program can safely improve heart function, exercise capacity, and quality of life in 25 participants.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
high-intensity interval training (HIIT)
What this could lead to
If successful, this could point toward a safe, home-based exercise program to improve fitness and quality of life for people with ANOCA.
What could go wrong
This is a very small, early-stage study with only 25 participants, so results may not apply to everyone. The exercise program is short (4 weeks) and may not lead to lasting improvements.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-85 * ANOCA (Anginal symptoms of chest pain or exertional dyspnea suspected to be from myocardial ischemia Invasive or CT coronary angiogram without obstructive epicardial CAD (≥50% left main or ≥70% other epicardial stenosis or fractional flow reserve ≤0.80) * Able to use the wearable and participate in a remote exercise program * Able to participate in intermittent high-intensity training. * Able to perform cardiopulmonary exercise testing (CPET) * Able to provide Health-related quality of life questionnaire (HRQOL) * Participants must be able to understand and provide informed consent in English and complete the study questionnaire in English Exclusion Criteria: * Systolic heart failure (LVEF \<50% or NYHA class III symptoms) * Prior myocardial infarction, coronary revascularization * Inability to safely undergo cardiopulmonary exercise testing, based on investigator's judgment * Pregnancy (due to unknown effects on CPET exercise markers) * Inability to provide informed consent * Life expectancy \<1 year * Prisoners * Cognitively impaired * Non-English speaking

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Conditions

The condition(s) this trial relates to.

coronary atherosclerosis Dyspnea MINOCA nonobstructive coronary artery disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atherosclerotic heart disease of native coronary artery MINOCA Shortness of breath

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Virginia Health System

    RECRUITING

    Charlottesville, Virginia, 22908, United States

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