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New drug cocktail aims to shrink Hard-to-Treat thyroid tumors

NCT ID NCT07193186

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 36 times

Summary

This phase II trial tests two drugs—anlotinib and benmelstobart—as a second-line treatment for people with advanced or metastatic differentiated thyroid cancer that has not responded to first-line therapy. The study will enroll 23 participants and measure how many see their tumors shrink. Treatment continues until the disease worsens or side effects become too severe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anlotinib and Benmelstobart

What this could lead to

If successful, this combination could offer a new second-line treatment option for people with advanced thyroid cancer that has stopped responding to initial therapy.

What could go wrong

This is a small, early-phase (phase II) study with only 23 participants. The treatment may not work for everyone and could cause side effects like fatigue, high blood pressure, or immune-related reactions.

Conditions

The condition(s) this trial relates to.

differentiated thyroid carcinoma thyroid cancer Thyroid Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.