Ankle glide vs. standard exercise: which helps diabetic stiffness?
NCT ID NCT07827625
First seen Sep 18, 2026 · Last updated Sep 18, 2026
Summary
People with type 2 diabetes often develop stiff ankles, pain, and walking problems. This trial compares two physiotherapy approaches: Mulligan Mobilization with Movement, where a therapist applies a gentle glide to the ankle during active movement, and conventional physiotherapy with range-of-motion exercises, calf raises, and stretching. Researchers will enroll 56 adults aged 50 to 70 who have had diabetes for more than five years and assign them randomly to one of the two programs for six weeks. The study measures changes in pain, ankle range of motion, walking speed, and quality of life to see which method works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Mulligan Mobilization with Movement, a hands-on physiotherapy technique that applies a gentle sustained glide to the ankle while the patient actively moves it
- What this could lead to
- If it works, this could give physiotherapists a clearer reason to choose one ankle technique over another for people with type 2 diabetes, potentially improving walking and comfort.
- What could go wrong
- The trial is small, with 56 participants, and lasts only six weeks, so any benefits may be modest or fade. Manual therapy can cause temporary soreness, and results may not apply to everyone with diabetes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 56 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 50-70 years * Both male and female * Diabetes Mellitus \> 5 years' duration * Willing to participate and provide informed consent * Pain rated between 3-7 on the Numeric Pain Rating Scale (NPRS) * Ankle dorsiflexion range of motion ≤10° on goniometric assessment Exclusion Criteria: * History of recent lower-limb surgery, fracture, or dislocation (\<6 months) * Active diabetic foot ulcer or Charcot foot * Any inflammatory joint disease (e.g., rheumatoid arthritis) * Congenital foot deformity * Diagnosed diabetic peripheral neuropathy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ibadat International University
RECRUITINGIslamabad, Federal, 47000, Pakistan
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