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Which anesthesia is safer for stroke treatment?

NCT ID NCT07422649

Knowledge-focused Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 481 stroke patients who had a procedure to remove a blood clot from their brain. Researchers compared those who received general anesthesia (fully asleep) versus sedation (awake but relaxed). They tracked death rates and recovery to see if one method was better. The goal was to find the safest approach for this emergency treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

481 people

The number who actually took part.

Started

Apr 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of adult patients with acute ischemic stroke who underwent mechanical thrombectomy at the University of Health Sciences Bakirkoy Dr. Sadi Konuk Training and Research Hospital between 2014 and 2018. Patients were treated within 6 hours of symptom onset and achieved successful angiographic reperfusion. Based on anesthesia records, patients were categorized according to anesthesia management as general anesthesia or sedoanalgesia.

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Acute ischemic stroke due to large vessel occlusion (MCA M1) * Mechanical thrombectomy performed within 6 hours of symptom onset * Pre-procedural TICI score 0-1 Exclusion Criteria: * Age ≥100 years * APACHE II score of 25 or higher * Glasgow Coma Scale score below 10 * Requirement for endotracheal intubation before the procedure * Patients discharged from the procedure to the intensive care unit while intubated * Time from symptom onset to procedure exceeding 6 hours

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Conditions

The condition(s) this trial relates to.

ischemic stroke middle cerebral artery infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute ischemic stroke

Contacts and locations

Locations

  • Fatma Acil

    Diyarbakır, Outside of the US, 21070, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.