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Could the speed of anesthesia gas shape lung recovery after nose surgery?

NCT ID NCT07758517

Knowledge-focused Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This observational study looks at whether the rate of fresh gas flow during general anesthesia influences how well the lungs stay open during and after septoplasty, a surgery to correct a deviated nasal septum. Researchers will compare two routine gas flow rates (1 L/min vs. 3 L/min) and track lung aeration using a lung ultrasound score at several points around the operation. The goal is to see if a lower gas flow might help reduce the mild lung collapse (atelectasis) that can occur under anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Fresh gas flow rate during inhalational anesthesia (1 L/min vs. 3 L/min)
What this could lead to
If a link is found, it could guide anesthesiologists to choose gas flow rates that better preserve lung function during surgery.
What could go wrong
This is a small observational study, so it cannot prove cause and effect. Results may not apply to other surgeries or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2 people

The number who actually took part.

Started

Jan 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of adults aged 18 to 65 years with American Society of Anesthesiologists physical status I or II who underwent elective septoplasty for nasal septal deviation under general anesthesia at Fatih Sultan Mehmet Training and Research Hospital. Eligible consenting participants were observed prospectively, and their perioperative clinical and lung ultrasound data were recorded. Fresh gas flow rates were selected by the attending anesthesiologist as part of routine clinical care.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years * Scheduled to undergo elective septoplasty for nasal septal deviation under general anesthesia * American Society of Anesthesiologists physical status I or II * Body mass index of 35 kg/m² or less * Provided written informed consent to participate Exclusion Criteria: * Acute respiratory tract infection within the preceding 15 days * Chronic pulmonary disease * Malignancy * Significant hepatic, renal, or cardiac disease * Limited ability to cooperate with the study assessments * Cerebrovascular or neuromuscular disease * Previous thoracic surgery * Chest wall deformity * Emergency surgery * History of clinically relevant allergy

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Conditions

The condition(s) this trial relates to.

Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atelectasis Nasal septal deviation

Contacts and locations

Locations

  • Istanbul Provincial Health Directorate Fatih Sultan Mehmet Training and Research Hospital

    Istanbul, 34000, Turkey (Türkiye)

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