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Can a new cage ease neck pain and restore function?

NCT ID NCT07743801

Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 04, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This trial tests whether a zero-profile anchored cage, used in anterior cervical discectomy and fusion, can improve outcomes for people with cervical degenerative disc disease. The study will enroll 30 adults aged 18-70 who have not had prior cervical spine surgery and whose symptoms (myelopathy or radiculopathy) have not improved with conservative care. Researchers will measure changes in neck and arm pain using the Visual Analog Scale and functional disability using the Neck Disability Index to see if the procedure helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Anterior cervical discectomy and fusion using a zero-profile anchored cage
What this could lead to
If successful, this could support the use of anchored cages as a safe and effective surgical option to relieve neck and arm pain and improve function in people with cervical disc disease.
What could go wrong
This is a small, single-center study with 30 participants, so results may not apply broadly. Surgery carries risks such as infection, implant issues, or nerve damage, and the cage may not outperform existing methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Started

Feb 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients of both genders aged between 18 and 70 years admitted to the Orthopedic Surgery department at Al-Azhar University Hospitals, presenting with symptomatic single or multi-level cervical degenerative disc disease (from C3-C4 to C6-C7) causing radiculopathy or myelopathy that is refractory to conservative medical treatment, and undergoing anterior cervical discectomy and fusion (ACDF) using a zero-profile anchored cage system

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-70 years old. * No prior cervical spine surgery. * Cervical degenerative disease: * Between C3-C4 to C6-C7. * Responsible for myelopathy or radiculopathy symptoms. * Resistant to conservative treatment. Exclusion Criteria: * Systemic, spinal, or localized infection. * Active rheumatoid arthritis or any other medical conditions that interfere with normal healing or increase surgical risk. * Known allergy to the implant materials used. * Malignancy and spinal metastasis. * Refusal to participate.

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Conditions

The condition(s) this trial relates to.

cervical disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervical disc disease Crevical disc disease

Contacts and locations

Locations

  • Alazhar University, Assiut

    Asyut, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.