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Braces breakthrough? simple wire stopper may replace screws in orthodontics

NCT ID NCT06416904

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a simple arch wire stopper can control molar movement as well as mini-screws during canine retraction in 26 post-pubertal female patients with dental protrusion. The goal was to see which method better prevents unwanted tooth movement. The trial is complete, but results are not yet widely available.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
arch wire stopper and mini-screw (devices)
What this could lead to
If successful, this could show that a simpler, less invasive device (arch wire stopper) works as well as mini-screws for controlling tooth movement during orthodontic treatment.
What could go wrong
This is a small, completed trial with only 26 participants, so results may not apply to all patients. The devices are for temporary use during treatment and do not address underlying dental issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Feb 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 25 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Post-pubertal female patients. * Cases with bimaxillary protrusion or Class II Division 1 malocclusion that require maxillary first premolars extraction. * Full permanent dentition (not necessitating third molars). * Good oral hygiene. Exclusion Criteria: * Medically compromised patients. * Active periodontal disease or obvious bone loss in the maxillary arch. * Patients with habits that are detrimental to dental occlusion (thumb sucking, tongue thrusting). * Smoking or any systemic diseases. * Chronic use of any medications including antibiotics, phenytoin, cyclosporine, anti-inflammatory drugs, systemic corticosteroids, and calcium channel blockers. All the above factors affect the rate of tooth movement * Previous orthodontic treatment. * Missing teeth.

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Conditions

The condition(s) this trial relates to.

malocclusion due to protuberant upper front teeth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic appliance complication

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University

    Cairo, 12613, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.