Could a common HIV drug be repurposed as an anal cream?
NCT ID NCT05334004
First seen Feb 11, 2026 · Last updated Jun 18, 2026 · Updated 17 times
Summary
This early-stage study tests whether a cream made from two HIV drugs (lopinavir/ritonavir) can be safely placed inside the anus to treat high-grade anal growths (AIN 2/3) in people living with HIV. About 21 participants will receive the cream for a few months and be followed for 40 weeks. The main goal is to find a safe dose, but researchers will also check if the growths shrink or disappear.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HIGH-GRADE ANAL INTRAEPITHELIAL NEOPLASIA are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
UW Digestive Health Center Anoscopy Clinic
RECRUITINGMadison, Wisconsin, 53705, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.