Hidden heart condition may be common in fracture patients
NCT ID NCT06527521
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how often amyloidosis, a rare disease where abnormal proteins build up in organs, occurs in people scheduled for trauma surgery. Researchers will use a checklist of warning signs (red flags) like age over 65, heart issues, or family history. About 246 adults will be checked to find out how many have the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 246 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients included in the waiting list for scheduled trauma surgery
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men and women included in the waiting list for scheduled trauma surgery with at least one of the following criteria defined as red flags: Over 65 years old; Possible family history of amyloidosis, Cardiac pathology: aortic stenosis, presence of left ventricular hypertrophy defined as interventricular septal thickness \> 12mm measured by echocardiography, history of previous brady- or tachyarrhythmias including cardiac conduction blocks, history of syncope or presyncope, pro BNP \> 300 in previous blood tests; History of sensory peripheral neuropathy; History of nephropathy without etiological diagnosis; History of liver disease without a clear cause. * Ability to cooperate in the necessary evaluations. * Signed informed consent for inclusion in the study, either by the participant or their legal representative. Exclusion Criteria: \- Participants previously diagnosed with amyloidosis cannot be included in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Consorci Sanitari Alt Penedes i Garraf-Hospital Sant Camil
RECRUITINGSant Pere de Ribes, Barcelona, 08810, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Banking blood and bone marrow to decode plasma cell disorders
- Can a single scan reveal hidden amyloid deposits across the body?
- A simple heart scan may unmask a hidden cause of heart failure
- A hidden warning in your wrist? surgery may reveal heart risk
- Can a daily pill keep a rare heart disease in check for the long haul?
- Heart drug acoramidis tested for Long-Term cardiac repair in rare amyloidosis