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Could a bladder rinse make emergency kidney stone treatment easier?

NCT ID NCT07617948

Symptom relief Sponsor: Beni-Suef University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether putting a drug called aminophylline into the bladder before placing a ureteral stent helps doctors get the stent past a blocking stone more easily. The trial involves 72 adults with sudden kidney failure from stones in a single working kidney. Half get the drug, half get a placebo, and the main goal is to see if the drug helps avoid a more invasive drainage procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Aminophylline
What this could lead to
If it works, this could make emergency stent placement easier and reduce the need for a more invasive kidney drainage procedure.
What could go wrong
This is a small Phase 2 trial with only 72 participants, so results may not apply broadly. The drug may not improve success rates and could cause side effects like allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 18 years or older. 2. Diagnosis of acute calculous anuria due to ureteral stone obstruction in a solitary functioning kidney. 3. Obstruction confirmed by pelvi-abdominal ultrasound and computed tomography of the urinary tract. 4. Clinical and laboratory evidence of acute renal impairment, including oliguria or anuria and serum creatinine \>2 mg/dL. 5. Ability to provide written informed consent. Exclusion Criteria: 1. Known hypersensitivity to aminophylline, theophylline, or other methylxanthines. 2. Evidence of active urinary tract infection or urosepsis. 3. Previous history of ureteral stricture or major urinary tract reconstructive surgery. 4. Hemodynamic instability requiring immediate life-saving measures before urological intervention. 5. Pregnancy.

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Conditions

The condition(s) this trial relates to.

acute kidney injury Ureteral Calculi ureterolithiasis urinary tract obstruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute calculous anuria Acute kidney injury Obstructive uropathy Ureteral calculi

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Urology- Beni-Suef University Hospitals

    RECRUITING

    Banī Suwayf, Beni Suweif Governorate, Egypt

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