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Can a gentamicin combo fight sepsis without harming kidneys?

NCT ID NCT06712641

First seen Mar 27, 2026 · Last updated Jun 06, 2026 · Updated 12 times

Summary

This study tests whether using a combination of gentamicin and a narrow-spectrum antibiotic is as safe and effective as using a broad-spectrum antibiotic alone for people with early sepsis. About 1,900 hospitalized adults will be randomly assigned to one of the two treatments. The goal is to see if the gentamicin approach causes fewer kidney problems and deaths while also reducing antibiotic resistance.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Akershus University Hospital

    RECRUITING

    Lørenskog, 1478, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Haukeland University Hospital

    NOT_YET_RECRUITING

    Bergen, Bergen, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lovisenberg Diakonal Hospital

    NOT_YET_RECRUITING

    Oslo, Oslo, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oslo University Hospital Ullevål

    RECRUITING

    Oslo, 0450, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Olav's Hospital

    NOT_YET_RECRUITING

    Trondheim, Trondheim, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.