Amniotic fluid secrets could protect preterm infants from deadly gut infections

NCT ID NCT07152106

Recruiting now Knowledge-focused Sponsor: Maxima Medical Center Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 22 times

Summary

This study collects amniotic fluid from 275 pregnant women delivering early (before 28 weeks) and at later stages to analyze its composition. Researchers aim to understand how fluid components and microbes influence gut development and the risk of severe conditions like necrotizing enterocolitis (NEC) and sepsis in newborns. The goal is to identify high-risk infants early and eventually develop targeted treatments to prevent disease.

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Contacts and locations

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Study contacts

Contact
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Amsterdam UMC
RECRUITING

Amsterdam, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••
Máxima Medical Center
RECRUITING

Veldhoven, Netherlands

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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CHORIOAMNIONITIS CHORIOAMNIONITIS AFFECTING FETUS OR NEWBORN FETAL GROWTH RESTRICTION (FGR) NECROTIZING ENTEROCOLITIS OF NEWBORN NEONATAL SEPSIS, EARLY-ONSET NEONATAL SEPSIS, LATE-ONSET PREMATURITY COMPLICATIONS PREMATURITY COMPLICATIONS PRETERM BIRTH COMPLICATION