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Major trial takes on Alzheimer's tau tangles with multiple drugs

NCT ID NCT06957418

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 31 times

Summary

This study tests whether new drugs that target tau protein in the brain can slow or stop Alzheimer's disease in its early stages. About 900 adults aged 50 to 80 with very mild or no symptoms will receive a tau drug, a combination of a tau drug and donanemab, or donanemab alone. The goal is to see if these treatments reduce tau buildup and preserve memory and thinking over 30 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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Conditions

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