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No treatment, just tracking: new study reveals true cost of early Alzheimer's

NCT ID NCT02951598

Knowledge-focused Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 1,400 people with early-stage Alzheimer's or mild cognitive impairment to understand how the disease affects healthcare costs and daily life over time. Participants are not given any experimental treatment. The goal is to gather information for research purposes only.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,400 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2016

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Presents within normal course of outpatient care for whom the physician deems to meet clinical criteria for MCI due to AD or mild AD dementia. * Fully informed written consent of the participant (or his/her legal representative). * Study partner who has frequent contact with the participant is willing to accompany the participant at the study observations. * Fully informed written consent of the study partner; this person must be willing to serve as study partner for at least 6 months of the year. * Able to communicate in English and/or US Spanish. * Able to provide evidence of amyloid testing. * Has an Mini-Mental State Examination (MMSE) score of 20 or greater. Exclusion Criteria: * Are currently enrolled in any other clinical trial involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study at baseline. * Are investigator site personnel directly affiliated with this study and/or their immediate families. Immediate family is defined as a spouse, parent, child, or sibling, whether biological or legally adopted. * Lack of evidence of amyloid positivity through pre-study test. Note: After baseline assessment, participants with amyloid negativity identified as part of the study will not continue in post-baseline assessments. * Are Lilly employees or are employees of any third-party organization (TPO) involved in study who require exclusion of their employees.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer disease Mild cognitive impairment

Contacts and locations

Locations

  • Adirondack Medical Center

    Lake Placid, New York, 12946, United States

  • Advanced Research Center

    Anaheim, California, 92805, United States

  • Alliance Research Centers

    Laguna Hills, California, 92653, United States

  • Alzheimer's Memory Center

    Charlotte, North Carolina, 28270, United States

  • American Health Network

    Franklin, Indiana, 46131, United States

  • American Research, LLC

    Jeffersonville, Indiana, 47130, United States

  • Asclepes Research Centers Florida

    Weeki Wachee, Florida, 34607, United States

  • Baptist Health Medical Group

    Lexington, Kentucky, 40503, United States

  • Biomed Research Institute

    Miami, Florida, 33126, United States

  • Breakthrough Clinical Trials

    San Bernardino, California, 92408, United States

  • California Neurological Services, Inc.

    Panorama City, California, 91402, United States

  • California Pharmaceutical Research Institute

    Anaheim, California, 92804, United States

  • Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • Clinical Innovations, Inc.

    Riverside, California, 92506, United States

  • Clinical Research Solutions, P.C.

    Knoxville, Tennessee, 37920, United States

  • Clinical Research of Homestead

    Homestead, Florida, 33030, United States

  • Clinical Research of South Florida

    Coral Gables, Florida, 33134, United States

  • Coastal Carolina Healthcare, P.A.

    New Bern, North Carolina, 28562, United States

  • Coastal Connecticut Research, LLC

    New London, Connecticut, 06320, United States

  • Colorado Neurological Institute

    Englewood, Colorado, 80113, United States

  • Combined Research Orlando Phase I-IV LLC

    Orlando, Florida, 32807, United States

  • Dallas Clinical Research

    Greenville, Texas, 75401, United States

  • Dayton Center for Neurological Disorders

    Centerville, Ohio, 45459, United States

  • Doctors Clinical Research

    Atlanta, Georgia, 30312, United States

  • Empire Clinical Research

    Miami Lakes, Florida, 33018, United States

  • Family Practice Center of Wooster

    Wooster, Ohio, 44691, United States

  • Florida International Research Center

    Miami, Florida, 33173, United States

  • Galiz Research

    Hialeah, Florida, 33016, United States

  • Genoma Research Group, Inc.

    Miami, Florida, 66135, United States

  • Global Clinical Trials

    Irvine, California, 92614, United States

  • HB Clinical Trials

    Santa Ana, California, 92704, United States

  • Hattiesburg Clinic

    Hattiesburg, Mississippi, 39401, United States

  • Havana Research Institute

    Pasadena, California, 91105, United States

  • Healthwise Medical Associates, PC

    Brooklyn, New York, 11206, United States

  • Heartland Research Associates

    Newton, Kansas, 67114, United States

  • Highlands Medical Associates, P.A.

    Highlands, Texas, 77562, United States

  • Indago Research & Health Center, Inc.

    Hialeah, Florida, 33012, United States

  • Infinite Clinical Research

    Doral, Florida, 33126, United States

  • Integrative Clinical Trials, LLC

    Brooklyn, New York, 11229, United States

  • International Research Partners, LLC.

    Doral, Florida, 33166, United States

  • Irvine Clinical Research Center

    Irvine, California, 92614, United States

  • JEM Research Institute

    Atlantis, Florida, 33462, United States

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida, 32216, United States

  • L&C Professional Medical Research Institute

    Miami, Florida, 33186, United States

  • Lakeside Life Center

    Carrollton, Texas, 75010, United States

  • Lynn Health Science Institute

    Oklahoma City, Oklahoma, 73112, United States

  • Medical Research Group of Central Florida

    Orange City, Florida, 32763, United States

  • Miami Jewish Health Systems

    Miami, Florida, 33137, United States

  • Mid Hudson Medical Research, PLLC

    New Windsor, New York, 12553, United States

  • NeuroMedical Clinic of Central Louisiana

    Alexandria, Louisiana, 71301, United States

  • New Life Medical Research Center, Inc

    Hialeah, Florida, 33012, United States

  • North Pointe Psychiatry

    Lewisville, Texas, 75057, United States

  • Onsite Clinical Solutions, LLC

    Charlotte, North Carolina, 28203, United States

  • Onsite Clinical Solutions, LLC

    Charlotte, North Carolina, 28226, United States

  • Pacific Clinical Studies, Inc

    Los Alamitos, California, 90720, United States

  • Premier Clinical Research

    Spokane, Washington, 99202, United States

  • Psych Care Consultants Research

    St Louis, Missouri, 63128, United States

  • Pyramid Clinical Research

    Monroe, New Jersey, 08831, United States

  • Research Alliance

    Clearwater, Florida, 33756, United States

  • Sarkis Clinical Trials

    Gainesville, Florida, 32607, United States

  • South Florida Clinical Trials

    Hialeah, Florida, 33016, United States

  • St. Agnes Medical Group

    Catonsville, Maryland, 21228, United States

  • Stedman Clinical Trials

    Tampa, Florida, 33613, United States

  • Sun Valley Research Center

    Imperial, California, 92251, United States

  • Suncoast Neuroscience Associates

    St. Petersburg, Florida, 33713, United States

  • Sunrise Medical Research

    Lauderdale Lakes, Florida, 33319, United States

  • The Clinical Research Group

    Frisco, Texas, 75035, United States

  • The Neurology Research Group, LLC

    Miami, Florida, 33176, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • Univ Of Texas Southwestern at Dallas Childrens Med Ctr

    Dallas, Texas, 75390, United States

  • Universal Neurological Care

    Jacksonville, Florida, 32216, United States

  • University Hills Clinical Research

    Irving, Texas, 75062, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • Van Buren Medical

    Hollywood, Florida, 33020, United States

  • Ventura Clinical Trials

    Ventura, California, 93003, United States

  • Visionary Investigators Network

    Aventura, Florida, 33180, United States

  • Wesley Neurology Clinic

    Cordova, Tennessee, 38018, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.