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New hope for kids with brittle bones: experimental drug enters final testing

NCT ID NCT06079359

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 28 times

Summary

This study tests a new medicine called ALXN1850 in 30 children aged 2 to 12 who have hypophosphatasia, a rare genetic condition that weakens bones. The drug is given as a shot under the skin and compared to a placebo (fake treatment) to see if it helps heal bone problems. All children in the study have not received the standard treatment before.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Baltimore, Maryland, 21287, United States

  • Research Site

    Kansas City, Missouri, 64108, United States

  • Research Site

    Durham, North Carolina, 27705, United States

  • Research Site

    Nedlands, 6009, Australia

  • Research Site

    Parkville, 3052, Australia

  • Research Site

    Brussels, 1020, Belgium

  • Research Site

    Brasília, 71625-009, Brazil

  • Research Site

    Porto Alegre, 90610-261, Brazil

  • Research Site

    Recife, 50740-465, Brazil

  • Research Site

    Salvador, 40050-410, Brazil

  • Research Site

    São Paulo, 01409-902, Brazil

  • Research Site

    São Paulo, 05403-900, Brazil

  • Research Site

    Calgary, Alberta, T2E 7Z4, Canada

  • Research Site

    Winnepeg, Manitoba, R3E 3P4, Canada

  • Research Site

    Beijing, 100045, China

  • Research Site

    Guangzhou, 510623, China

  • Research Site

    Shanghai, 2000127, China

  • Research Site

    Shenzhen, 518053, China

  • Research Site

    Helsinki, 00290, Finland

  • Research Site

    Ashkelon, 7830604, Israel

  • Research Site

    Chihuahua City, 31238, Mexico

  • Research Site

    Lodz, 93-338, Poland

  • Research Site

    Bucharest, 011863, Romania

  • Research Site

    Madrid, 28046, Spain

  • Research Site

    Vitoria-Gasteiz, 01009, Spain

  • Research Site

    Stockholm, 17176, Sweden

  • Research Site

    Taipei, 100, Taiwan

  • Research Site

    Ankara, 06560, Turkey (Türkiye)

  • Research Site

    Bursa, 16059, Turkey (Türkiye)

  • Research Site

    Erzurum, 25240, Turkey (Türkiye)

  • Research Site

    Istanbul, 34899, Turkey (Türkiye)

  • Research Site

    Birmingham, B4 6NH, United Kingdom

Conditions

Explore the condition pages connected to this study.