HYPOPHOSPHATASIA
Clinical trials for HYPOPHOSPHATASIA explained in plain language.
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New study tracks immune risk in rare bone disease drug
Knowledge-focused Recruiting nowThis study follows 30 people with hypophosphatasia (HPP) who are taking the medication asfotase alfa. Researchers want to see if the body's immune system can make the drug less effective or cause serious allergic reactions. Participants will be observed for at least 5 years to tr…
Matched conditions: HYPOPHOSPHATASIA
Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated May 26, 2026 07:24 UTC
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Rare bone disease under the microscope: new study watches patients over time
Knowledge-focused Recruiting nowThis study follows 200 children and adults with hypophosphatasia (HPP), a rare genetic disorder that weakens bones and teeth. Researchers will collect medical history, track how the disease changes over time, and measure quality of life. The goal is to better understand HPP and i…
Matched conditions: HYPOPHOSPHATASIA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 26, 2026 07:22 UTC
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Russian study to track rare bone disease without treatment
Knowledge-focused Recruiting nowThis study aims to observe the natural course of hypophosphatasia (HPP) in 55 children and adults in Russia who have not received enzyme-replacement therapy. Researchers will track symptoms, lab results, and quality of life to better understand how the disease unfolds over time. …
Matched conditions: HYPOPHOSPHATASIA
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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New registry aims to speed up diagnosis of rare bone disease
Knowledge-focused Recruiting nowThis study follows 130 adults with hypophosphatasia, a rare bone disease, to track how they are diagnosed and what medical events occur. Researchers want to find ways to reduce the long delay between first symptoms and diagnosis. Participants are not given any treatment; the stud…
Matched conditions: HYPOPHOSPHATASIA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 07, 2026 18:39 UTC