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New bone-saving materials tested after tooth extraction

NCT ID NCT05902689

Disease control Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study tested two materials—sticky bone and Bio-Oss collagen—to preserve the jawbone after a tooth is pulled. 42 adults who needed a tooth extraction received either natural healing, Bio-Oss collagen, or sticky bone placed in the socket. The goal was to see which method best maintained bone width and height for future dental implants. Results help dentists choose the best option to keep the jawbone strong.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Jun 2023

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. The presence of one adjacent tooth at the extraction site 2. Adequate oral hygiene (plaque index \<20%;bleeding on probing \<25% ) 3. Need for tooth extraction due to endodontic，periapical or periodontal disease. 4. Presence of ≥ 2 mm of keratinized tissue 5. the extraction sockets have no more than 50% of buccal alveolar bone loss(Integrity of alveolar bone walls) Exclusion Criteria: 1. Pregnancy or lactation 2. Smoking more than 10 cigarettes per day 3. with no evidence of acute infection such as severe swelling, suppuration at the extraction site 4. Uncontrolled periodontal disease 5. Existence of bone metabolic disease 6. history of malignancy, radiotherapy, or chemotherapy in the past 5 years 7. Administration of bisphosphonates 8. long-term use of NSAIDs 9. Alcohol or drug abuse 10. Infectious disease, such as hepatitis or human immunodeficiency virus (HIV) and/or acquired immunodeficiency syndrome (AIDS) 11. Uncontrolled severe diabetes.( hemoglobin A1c \>6.7%)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar bone resorption

Contacts and locations

Locations

  • 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China

    Hangzhou, Zhejiang, China

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