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Mountain air or mental strain? new study tests Altitude's effect on anxiety

NCT ID NCT05323864

Knowledge-focused Sponsor: Universitaet Innsbruck Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how low oxygen levels (like at high altitudes) affect mood and anxiety in people with depression or anxiety disorders compared to healthy individuals. 68 participants will spend six hours in a special chamber that simulates 3,800 meters altitude, and their feelings, stress, and blood markers will be measured. The goal is to gather information to create safety guidelines for people with mental illnesses who travel to high places.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
normobaric hypoxia (simulated high altitude)
What this could lead to
If successful, this could help create safety guidelines for people with mental illnesses who travel to high altitudes.
What could go wrong
This is a small, early-stage study (68 participants) in a lab, not real mountains. Results may not apply to everyone or predict real-world risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 68 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2023

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * sufficient command of the German language * no psychotic or cognitive disorders * patients suffering from anxious-depressive symptoms (meeting the cut off points of light-medium in the screening for anxiety and depression symptoms) Exclusion Criteria: * pregnant or breastfeeding * permanent residence above 1000m * overnight stays at altitudes above 2500m in the previous month * exposure to 2500m or higher two weeks prior to the six-hour hypoxic exposure

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Conditions

The condition(s) this trial relates to.

altitude sickness anxiety disorder Depression Hypoxia mental disorder mixed anxiety and depressive disorder psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hypoxia Mental disorder

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Innsbruck, Department of Sport Science

    RECRUITING

    Innsbruck, Tyrol, 6020, Austria

More trials for these conditions

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