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New drug combo tested for safety in advanced breast cancer

NCT ID NCT05631795

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This study tested the safety of combining two drugs, alpelisib and fulvestrant, in 40 men and post-menopausal women with a certain type of advanced breast cancer (HR-positive, HER2-negative) that has a PIK3CA mutation and has stopped responding to hormone therapy. The goal was to see how many people had side effects during treatment. The study is complete and focused on safety, not on curing the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Guwahati, Assam, 781016, India

  • Novartis Investigative Site

    Surat, Gujarat, 395009, India

  • Novartis Investigative Site

    Thalassery, Kerala, 670103, India

  • Novartis Investigative Site

    Trivandrum, Kerala, 695 011, India

  • Novartis Investigative Site

    Bhopal, Madhya Pradesh, 462001, India

  • Novartis Investigative Site

    Mumbai, Maharashtra, 400 012, India

  • Novartis Investigative Site

    Nagpur, Maharashtra, 440001, India

  • Novartis Investigative Site

    Pune, Maharashtra, 411040, India

  • Novartis Investigative Site

    New Delhi, National Capital Territory of Delhi, 110029, India

  • Novartis Investigative Site

    Hyderabad, Telangana, 500004, India

  • Novartis Investigative Site

    Ahmedabad, 380016, India

  • Novartis Investigative Site

    Kolkata, 700026, India

Conditions

Explore the condition pages connected to this study.