New drug combo shows promise for Hard-to-Treat breast cancer
NCT ID NCT05143229
First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 29 times
Summary
This early-stage trial tests the safety and best dose of combining two drugs, alpelisib and sacituzumab govitecan, for people with advanced HER2-negative breast cancer that has spread or come back. The study includes 18 adults with this type of cancer. The main goal is to find the safest dose and see how the body handles the drugs.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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The University of Kansas Cancer Center
Westwood, Kansas, 66205, United States
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The University of Kansas Cancer Center - Indian Creek
Overland Park, Kansas, 66211, United States
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The University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri, 64064, United States
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The University of Kansas Cancer Center - North
Kansas City, Missouri, 64154, United States
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The University of Kansas Cancer Center - North Kansas City Hospital
Kansas City, Missouri, 64116, United States
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The University of Kansas Cancer Center - Overland Park
Overland Park, Kansas, 66210, United States
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The University of Kansas Clinical Research Center
Fairway, Kansas, 66205, United States
Conditions
Explore the condition pages connected to this study.