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New pill shows promise in early hepatitis b trial

NCT ID NCT04536337

First seen Nov 21, 2025 · Last updated May 22, 2026 · Updated 25 times

Summary

This early-stage study tested a new oral drug called ALG-000184 in 165 people, including healthy volunteers and patients with chronic hepatitis B. The main goals were to check if the drug is safe and well-tolerated, and to see if it can lower hepatitis B virus levels in the blood. Some patients also received the drug together with a standard treatment (entecavir) for up to 96 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ACS

    Auckland, New Zealand

  • CAP Research

    Quatre Bornes, Mauritius, 72218, Mauritius

  • Nanfang Hospital of Southern Medical University

    Guangzhou, Guangdong, China

  • PMSI Republican Clinical Hospital "T. Mosneaga", ARENSIA Exploratory Medicine Phase I Unit

    Chisinau, Moldova

  • Prince of Wales

    Shatin, Hong Kong

  • Queen Mary Hospital

    Hong Kong, Hong Kong

  • Saint Vincent's Hospital Melbourne

    Fitzroy, Victoria, 3065, Australia

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Second Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

  • Western Health

    Footscray, Victoria, 3011, Australia

Conditions

Explore the condition pages connected to this study.