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Lung cancer drug alectinib put to the test in Dose-Finding trial

NCT ID NCT05713006

First seen Apr 22, 2026 · Last updated Jun 23, 2026 · Updated 15 times

Summary

This study is testing the drug alectinib in 45 Mexican patients with advanced ALK-positive non-small cell lung cancer. In the first phase, patients receive increasing doses every 21 days to measure drug levels and safety. In the second phase, the chosen dose is given to see how well it shrinks tumors. The goal is to find the best dose for this population.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Thoracic Oncology Unit and Personalized Medicine Laboratory, Instituto Nacional de Cancerología

    RECRUITING

    Mexico City, Mexico City, 14080, Mexico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

alectinib (Alecensa)

What this could lead to

If successful, this could help determine the optimal alectinib dose for ALK-positive lung cancer patients, potentially improving treatment outcomes.

What could go wrong

This is an early-phase trial with only 45 participants, so results may not apply to all patients. Dose escalation may cause side effects, and the drug may not shrink tumors as hoped.

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.