Study reveals what happens when you mix booze and High-Potency weed
NCT ID NCT05999344
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how drinking alcohol and using high-THC cannabis concentrates together affects people. 146 heavy drinkers who also use cannabis regularly took part. Researchers measured things like blood alcohol level, heart rate, and how impaired they felt, depending on whether they drank first or used cannabis first. The goal was to understand how order and THC content change the experience, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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146 people
The number who actually took part.
- Started
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Dec 2021
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. 21-65 years old, 2. Heavy drinkers (for men, \>4 drinks in one occasion, or \>14 drinks per week; for women, \>3 drinks in one occasion, or \>7 drinks per week) 3. Regular users of legal-market cannabis (at least 3x/week in past 3 months) 4. Have experience using cannabis concentrates within the last year 5. Willing to obtain a concentrate product of their choice for use in the study. Exclusion Criteria: 1. Diagnosed with or seeking treatment for alcohol use disorder (AUD) or other substance use disorder (SUD) 2. Pregnant, breastfeeding or trying to become pregnant 3. Meet criteria for psychotic, bipolar or major depressive disorder with suicidal ideation, or history of these disorders 4. Current use of psychotropic (except anti-depressants) or steroid medications 5. Report illicit drug use in past 60-days or fail drug screen (drug screen tests for the presence of amphetamines, benzodiazepines, cocaine, THC, methamphetamine and opioids; only THC is allowed to be present in urine in order to be eligible to participate in the study 6. Major medical condition contraindicating alcohol and/or cannabis consumption (e.g., liver disease, heart disease, or being told by a doctor that it is unsafe to consume alcohol or cannabis due to a medical condition) 7. Have participated in another research study in the past 8 weeks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Colorado State University
Fort Collins, Colorado, 80523, United States
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