Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New blood test aims to catch lung transplant problems early

NCT ID NCT05050955

Knowledge-focused Sponsor: CareDx Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a blood test called AlloSure Lung in 550 lung transplant patients. The test looks for DNA from the donor lung in the patient's blood, which could signal rejection or infection. Researchers want to see how accurate the test is compared to standard monitoring. The study is observational, meaning it only watches and measures—it does not test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
AlloSure Lung (donor-derived cell-free DNA blood test)
What this could lead to
If successful, this blood test could help doctors spot lung transplant rejection or infection earlier, potentially improving patient outcomes.
What could go wrong
This is an observational registry, not a treatment trial. The test may not prove accurate enough to change standard care, and results may not apply to all transplant patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

550 people

The number who actually took part.

Started

Oct 2021

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All lung transplant patients without exclusion criteria will be eligible to enter the study. Patients will be approached by the study team at the time of listing or at the time of transplant or within 90 days post-transplant to discuss the trial, consent and enrollment.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Unilateral or Bilateral, deceased-donor, initial or re-transplant 2. ≤ 90 days post-transplant 3. Ability to understand and provide informed consent and adhere to laboratory surveillance schedule 4. Patients who have LungCare initiated within 30 days of signing the informed consent form Exclusion Criteria: 1. Multi-organ transplants 2. Pregnancy 3. Active malignancy

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Lung transplant failure and rejection are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Rejection, Psychology transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung transplant failure and rejection Lung transplant infection Lung transplant; complications

Contacts and locations

Locations

  • AdventHealth Orlando

    Orlando, Florida, 32804, United States

  • Brigham and Womens Hospital

    Boston, Massachusetts, 02115, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Columbia University Medical Center

    New York, New York, 10027, United States

  • Inova

    Falls Church, Virginia, 22042, United States

  • Loyola University Medical School

    Maywood, Illinois, 60153, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • St. Joseph's Hospital & Medical Center

    Phoenix, Arizona, 85013, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • Toronto General Hospital

    Toronto, Ontario, M5G 2C4, Canada

  • UT Health/ Memorial Hermann Hospital

    Houston, Texas, 77030, United States

  • University of Alabama (UAB)

    Birmingham, Alabama, 35233, United States

  • University of CO Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • University of California (UCSF) School of Medicine

    San Francisco, California, 94143, United States

  • University of Louisville Health

    Louisville, Kentucky, 40202, United States

  • University of Mayland

    Baltimore, Maryland, 21201, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Wisconsin Madison

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Washington University-Barnes Jewish Hospital

    St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.