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New hope for hard-to-treat cancers: drug combo enters human trials

NCT ID NCT07392736

First seen Feb 06, 2026 · Last updated May 24, 2026 · Updated 17 times

Summary

This study is testing a new combination of two drugs (AL8326 and toripalimab) in people with advanced solid tumors that have stopped responding to standard therapy or have no other treatment options. The trial has two parts: first, finding the safest and most effective dose, and second, measuring how well the combination shrinks tumors. About 228 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, 515000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fujian Cancer Hospital

    RECRUITING

    Fuzhou, Fujian, 350001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Guangxi Medical University Cancer Hospital

    RECRUITING

    Nanning, Guangxi, 530021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hunan Cancer Hospital

    RECRUITING

    Hunan, Changsha, 410000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Liuzhou Workers' Hospital

    RECRUITING

    Liuzhou, Guangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National GCP Center for Anticancer Drugs,The Independent Ethics Committee

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • SIR RUN RUN SHAW Hospital Zhejiang University School Of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310016, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Cancer Hospital of the Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Guilin Medical Universty

    RECRUITING

    Guilin, Guangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xi'an Jiaotong University

    RECRUITING

    Xi’an, Shanxi, 710000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    RECRUITING

    Nanning, Guangxi, 530000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yuebei People's Hospital

    RECRUITING

    Shaoguan, Guangdong, 51200, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhejiang Cancer Hospital

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.