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Massive latin american study aims to improve dialysis for critically ill kidney patients

NCT ID NCT07262320

Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is observing 1,000 critically ill adults in Latin American ICUs who need dialysis for severe acute kidney injury. Researchers will track treatments, outcomes, and country differences to understand what works best. The goal is to gather data that can improve care and guide future research.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal which care practices improve survival for ICU patients with severe acute kidney injury needing dialysis in Latin America.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may vary widely across countries and may not apply to other regions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Critically ill patients with AKI requiring RRT in Latin American countries

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patient (≥18) admitted to the ICU * First ICU admission during current hospitalization * Diagnosis of acute kidney injury stage 3 according to KDIGO guidelines * RRT initiated no earlier than 3 days before or no later than 7 days after ICU admission Exclusion Criteria: * Transfer from outside hospital with ongoing RRT * RRT exposure of less than 2 days (if CRRT or PD was provided) or less than 2 HD/SLED sessions * Kidney failure (ESRD) patients on maintenance dialysis * Kidney transplant recipients * Previous or new diagnosis of glomerulonephritis

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Conditions

The condition(s) this trial relates to.

acute kidney injury wild type ABeta2M amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury AKI Critically ill acute kidney injury Dialysis Renal replacement therapy Renal replacement therapy for acute kidney injury in icu

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    15 sites in 9 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ana Nery Hospital

    NOT_YET_RECRUITING

    Bahia, Brazil

  • DIALNEF

    NOT_YET_RECRUITING

    Quito, Ecuador

  • Fundación Cardioinfantil

    RECRUITING

    Bogotá, Colombia

  • Hospital Civil de Guadalajara

    RECRUITING

    Guadalajara, Mexico

  • Hospital General de México Dr Eduardo Liceaga

    NOT_YET_RECRUITING

    Mexico City, Mexico

  • Hospital General de la Plaza de la Salud

    RECRUITING

    Santo Domingo, Dominican Republic

  • Hospital Las Higueras

    NOT_YET_RECRUITING

    Talcahuano, Chile

  • Hospital Nacional Arzobispo Loayza

    RECRUITING

    Lima, Peru

  • Hospital Obrero No 2

    RECRUITING

    Cochabamba, Bolivia

  • Hospital San Jose de Popayan

    RECRUITING

    Popayán, Colombia

  • Hospital Sao Lucas da PUCRS

    NOT_YET_RECRUITING

    Porto Alegre, Brazil

  • Hospital Universitario "José Eleuterio González"

    RECRUITING

    Monterrey, Mexico

  • Hospital das Clínicas da Universidade de São Paulo

    NOT_YET_RECRUITING

    São Paulo, Brazil

  • Instituto Guatemalteco de Seguridad Social

    NOT_YET_RECRUITING

    Guatemala City, Guatemala

  • Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

    RECRUITING

    Mexico City, Mexico

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