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New combo therapy targets advanced lung cancer in Mid-Stage trial

NCT ID NCT04736823

First seen Mar 14, 2026 · Last updated May 24, 2026 · Updated 9 times

Summary

This phase II study tests a new drug called AK112 (a bispecific antibody that targets PD1 and VEGF) combined with standard chemotherapy in 265 people with advanced non-small cell lung cancer (stage IIIB/C or IV). The goal is to see if the combination shrinks tumors and how safe it is. Participants must be 18-75 years old and in fairly good health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sun Yat-Sen University Cancer Center

    Guanzhou, Guangdong, China

Conditions

Explore the condition pages connected to this study.