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Cleaner air, healthier heart? new trial tests HEPA filters against atherosclerosis

NCT ID NCT05867381

First seen Jun 10, 2026 · Last updated Jun 19, 2026 · Updated 2 times

Summary

This study tests whether using HEPA air filters at home can slow the progression of heart disease in 112 adults aged 65–84 with a history of ischemic heart disease. Participants will use a real HEPA filter and a sham filter for several months each, and researchers will measure changes in blood pressure, artery stiffness, and blood markers. The goal is to see if reducing indoor air pollution can help manage heart disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Keck School of Medicine, University of Southern California

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HEPA air filter

What this could lead to

If it works, this could show that cleaning indoor air helps manage heart disease and reduce related risks.

What could go wrong

This is a small, early-stage trial focused on short-term changes in blood pressure and blood markers, not on heart attacks or survival. The results may not apply to everyone.

Conditions

The condition(s) this trial relates to.

Atherosclerosis Cardiovascular Diseases myocardial ischemia Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.