AI could predict the perfect moment to take ICU patients off ventilators
NCT ID NCT07658131
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an artificial intelligence program designed to predict the best time to remove a breathing tube (extubation) from patients in intensive care. Researchers will use data from 1500 adults who were on a ventilator for at least 72 hours across four hospitals. The AI analyzes routine clinical information like ventilator settings and vital signs to forecast successful extubation. The goal is to see how accurately the tool performs compared to standard medical judgment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-aided weaning software
- What this could lead to
- If successful, this AI tool could help doctors decide when to safely remove a breathing tube, potentially reducing time on ventilators and improving outcomes for critically ill patients.
- What could go wrong
- This is a retrospective study using existing data, not a live trial. The AI may not perform as well in real-world settings or on different patient populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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1,500 people
The number who actually took part.
- Started
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Jan 2020
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with acute respiratory failure who were admitted to participating hospitals between January 2022 and December 2024 and required invasive mechanical ventilation for at least 24 hours. This is a retrospective study using existing clinical and imaging data for model validation.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients aged 20 years or older. * Admitted to the intensive care unit (ICU) at one of the participating hospitals between January 1, 2020 and December 31, 2024. * Received invasive mechanical ventilation for at least 72 hours. * Availability of de-identified clinical data required for model validation. Exclusion Criteria: * Patients who did not receive invasive mechanical ventilation. * Duration of mechanical ventilation less than 72 hours. * Missing key clinical variables required for model validation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Taichung Veterans General Hospital
Taichung, Taiwan
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Other studies related to the condition(s) this trial covers.
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