AI takes on the Doctor's note: can machines write clear health advice?
NCT ID NCT06997107
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
This study asks whether generative AI can produce patient education messages that match the quality of messages written by human health experts. Researchers generate short and long health messages on various topics using both ChatGPT 4.0 and human experts in primary care or public health. Diverse panels of patients and providers then rate the messages on clarity, understandability, relevance, and usefulness, with attention to how accessible the messages are across different socioeconomic groups. The goal is to learn whether AI can help primary care deliver trusted health information and reduce the burden on strained healthcare teams.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Health messages written by AI (ChatGPT 4.0) compared with messages written by human health experts
- What this could lead to
- If AI-written messages rate as well as human-written ones, primary care clinics could produce clear patient education faster and at lower cost, which may free up staff time and help reach more patients.
- What could go wrong
- This is a small study of 56 reviewers, and people rating messages may score them differently than real patients reading them at home. AI messages can also contain errors or miss cultural context, so high ratings would not guarantee safe use in every setting.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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56 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Content team members: Content team members must have an expertise in primary care, public health, or health communication. The investigators aim to recruit at least two or three members whose mother tongue is French. * Providers' review panel: The investigators will recruit a diverse group of primary care providers. All providers who provide comprehensive care in Canada and will be eligible to participate. They must be proficient in either written English or French. They must be able to consent to participate in this study. * Patients' review panel: The investigators will recruit a diverse group of patients. All must be aged 18 years or older and be proficient in either written English or French. They must be able to consent to participate in this study. Exclusion Criteria: * Content team members, primary care providers, or patients who cannot write (content team members) or read (review panels) in either French or English will be excluded. Primary care providers or patients who do not have an email address, a computer or a cellphone to complete the evaluations on REDCap will also be excluded. The investigators will not include minors or patients who cannot provide informed consent themselves, such as those with advanced dementia.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut du Savoir Montfort
Ottawa, Ontario, K1N 0T2, Canada
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