AI vs. doctors: who decides when to trigger ovulation in IVF?
NCT ID NCT07110285
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares decisions made by doctors versus an artificial intelligence algorithm on when to trigger ovulation during IVF. The goal is to see which approach leads to collecting more mature eggs. 180 participants undergoing IVF with a specific protocol will be randomly assigned to either the AI or doctor decision group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Artificial intelligence-based algorithm
- What this could lead to
- If successful, this could show that AI helps doctors choose the best time to trigger ovulation, potentially increasing the number of mature eggs retrieved in IVF.
- What could go wrong
- This is a relatively small, early-stage study. The AI may not outperform doctors, and results may not apply to all IVF patients or protocols.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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May 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients undergoing an ovarian stimulation cycle utilizing the GnRH antagonist protocol for oocyte cryopreservation or for fertilization via intracytoplasmic sperm injection (ICSI) (any treatment where oocytes are denuded and maturity may be assessed). Exclusion Criteria: * Loss to follow-up, patient retracts consent to participate
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Herzliya Medical Center
RECRUITINGHerzliya, 74077, Israel
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