Red light therapy for IVF embryos: a new hope for fertility?
NCT ID NCT07311928
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether shining a special red light on embryos during IVF can help them grow better. As women age, the energy centers in their cells (mitochondria) weaken, making it harder for embryos to develop. The light therapy aims to boost that energy. Researchers will compare embryos from 200 women who receive the light treatment versus those who don't, looking at how many become usable for transfer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- photobiomodulation (low-level red light therapy)
- What this could lead to
- If it works, this could improve the number of usable embryos for IVF, potentially increasing pregnancy chances for older women.
- What could go wrong
- This is an early-stage study focused on embryo development, not live birth rates. The light therapy may not improve outcomes, and results may not apply to all IVF patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Dec 2025
- Expected to finish
-
Jun 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 48 years
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female age between 18-48 years at time of IVF/ICSI cycle * Undergoing blastocyst culture and PGT-A * Using own oocytes * Have at least two fertilized eggs available for randomization * Consenting to embryo-level randomization * Plan to transfer euploid embryo within 6 months Exclusion Criteria: * Use of donor eggs * Known uterine or genetic anomalies * Refusal of randomization or request for non-standard handling
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Columbia University Fertility Center
New York, New York, 10019, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Light therapy may boost IVF success for older women
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