AI predicts hidden glaucoma risk after LASIK in 10,000-Patient study
NCT ID NCT07544615
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses artificial intelligence to predict true eye pressure after corneal refractive surgery like LASIK or SMILE. Standard eye pressure measurements can be falsely low after these surgeries, masking glaucoma risk. Researchers will analyze data from over 10,000 participants to train a machine learning model that estimates actual intraocular pressure, helping doctors detect steroid-induced glaucoma early and guide treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,030 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2018
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
myopia and Myopic Astigmatism
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Normal preoperative IOP, no glaucoma or suspected glaucoma. 2. Corneal thickness ≥ 480 μm. 3. Discontinuation of rigid gas permeable contact lenses for ≥3 months and soft contact lenses for ≥2 weeks prior to examination. 4. Clear cornea, no corneal leukoma, no history of ocular trauma. 5. No previous ocular surgery. 6. Willingness to participate and comply with all study examinations and procedures. Exclusion Criteria: \- 1. Severe psychiatric disorders. 2. Ocular hypertension, suspected glaucoma, or glaucoma. 3. Concurrent other ocular diseases (e.g., corneal opacity, uveitis). 4. History of ocular surgery, trauma, or contact lens wear (as per inclusion criterion #3). 5\. Nystagmus or inability to cooperate with examinations. 6. Presence of other ocular surface diseases, dry eye syndrome, fundus diseases, or systemic diseases affecting the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tianjin Eye hospital
Tianjin, Tianjin Municipality, 300020, China
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Other studies related to the condition(s) this trial covers.
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