AI and gel join forces to close ugly gaps in failed dental implants
NCT ID NCT07586228
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using hyaluronic acid (a natural gel) with AI-guided implant placement can improve the appearance of black triangles (gaps between teeth and gums) after a dental implant fails. The trial will enroll 32 adults with a failed front tooth implant and a black triangle of at least 2 mm. Participants will receive the new technique, and researchers will measure how well the gum fills in and overall look of the area.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 32 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults (20-50) years old. * Single rooted maxillary anterior teeth with hopeless prognosis. * Periodontally compromised but with \>50% remaining bone. * Presence of black triangle ≥2 mm. * Systemically healthy. Exclusion Criteria: * Medically compromised patients and systemic conditions that complicate implant placement as uncontrolled diabetes, osteoporosis. * Alcoholic and Smokers patients. * Pregnant or lactating women. * Acute Pathology or infection at implant site * Patients with a history of chemotherapy, radiotherapy in head and/or neck region. * Patients on bisphosphonate or steroids therapy.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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faculty of dentistry, kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, 214312, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Dental implant showdown: which connection design saves more bone?
- 3D-Printed short implants could offer new option for jawbone loss
- Short implants, long promise: 5-Year study tests durability in tough jaw spots
- Vitamin d deficiency may undermine dental implants — trial tests if supplements can fix it
- Gum graft boost: platelet gel or probiotics for better implants?