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AI could spot hidden brain aneurysms before they burst

NCT ID NCT06118840

Diagnosis Sponsor: Jinling Hospital, China Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether an artificial intelligence (AI) model can help doctors find brain aneurysms more accurately on CT scans. Over 6,400 adults in China will have their scans reviewed by radiologists with either a real AI or a sham AI that gives no real help. The goal is to see if the AI improves detection rates and patient outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
AI software (True-AI deep-learning model) for detecting brain aneurysms on CT scans
What this could lead to
If successful, this AI could help doctors spot brain aneurysms earlier and more accurately, potentially preventing life-threatening ruptures.
What could go wrong
This is a diagnostic accuracy study, not a treatment trial. The AI may not improve real-world outcomes, and results may not apply outside China.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 6,450 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult inpatients and outpatients who are scheduled for head CTA scanning. Exclusion Criteria: * Age under 18 years. * Patients with contraindications to CTA. * Modified Rankin Scale (mRS) score \> 3. * Refuse to sign informed consent. * Participation in other clinical studies of intracranial aneurysms. * Patients with failed head CTA scanning or incomplete image data, or poor image quality.

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Conditions

The condition(s) this trial relates to.

brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CT angiography Deep learning Double bind interaction Intracranial aneurysm

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    21 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Affiliated Hospital of Xuzhou Medical University

    RECRUITING

    Xuzhou, Jiangsu, China

  • BenQ Medical Center, Affiliated BenQ Hospital of Medical School, Nanjing Medical University

    RECRUITING

    Nanjing, China

  • First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, China

  • First People's Hospital of Lianyungang

    RECRUITING

    Lianyungang, China

  • General Hospital of Ningxia Medical University

    RECRUITING

    Yinchuan, China

  • Guizhou Provincial People's Hospital

    RECRUITING

    Guiyang, Guizhou, China

  • Hainan General Hospital

    RECRUITING

    Haikou, China

  • Long Gang Central Hospital of Shenzhen

    RECRUITING

    Shenzhen, China

  • Ma'anshan People's Hospital

    RECRUITING

    Ma’anshan, China

  • Research Institute Of Medical Imaging Jinling Hospital

    RECRUITING

    Nanjing, Jiangsu, 210018, China

  • Shandong Provincial Hospital Affiliated to Shandong First Medical University

    RECRUITING

    Jinan, Shandong, China

  • Shiyan People's Hospital

    RECRUITING

    Shiyan, Hubei, China

  • The Affiliated Suqian First Hospital of Nanjing Medical University

    RECRUITING

    Suqian, China

  • The First Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, China

  • The First Affiliated Hospital of University of Science and Technology of China

    RECRUITING

    Hefei, Anhui, China

  • The First Affiliated Hospital of Wannan Medical College

    RECRUITING

    Wuhu, Anhui, China

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, China

  • The First People's Hospital of Kashgar Region

    RECRUITING

    Kashgar, China

  • Tianjin Medical University General Hospital

    RECRUITING

    Tianjin, China

  • University Second Hospital

    RECRUITING

    Lanzhou, China

  • Yidu Central Hospital Affiliated to Shandong Second Medical University

    RECRUITING

    Weifang, Shandong, China

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