AI reads your Heart's electrical signals to find hidden blockages
NCT ID NCT06528821
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study enrolls 800 patients having heart attacks to test an artificial intelligence model that reads standard 12-lead ECGs. The AI aims to detect which artery is blocked and how severely blood flow is reduced, at the moment of a heart catheterization. If accurate, this could help doctors decide on treatment faster and more precisely.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Artificial intelligence (AI) model analyzing standard 12-lead electrocardiograms (ECGs)
- What this could lead to
- If successful, this AI could help doctors quickly identify which artery is blocked during a heart attack, leading to faster, more targeted treatment.
- What could go wrong
- This is an observational registry, not a treatment trial. The AI's accuracy may vary across different patient groups, and it has not yet been tested in real-time clinical decision-making.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 800 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults (18 or older) with acute coronary syndrome undergoing clinically indicated invasive coronary angiography, with a standard 12-lead ECG performed at invasive coronary angiogram before percutaneous coronary intervention (maximum within 15 min before vascular access)
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with acute coronary syndromes undergoing invasive coronary angiography as clinically indicated. * Availability of a standard 12-lead ECG performed at invasive coronary angiogram before percutaneous coronary intervention (maximum within 15 min before vascular access). * Age ≥18 years. Exclusion Criteria: * Individuals presenting for a non-emergent (elective) cardiac catheterization. * Individuals presenting with chronic coronary syndrome (CCS) or stable angina symptoms. * Individuals without symptoms suspicious for acute coronary syndromes. * Individuals with contraindications for cardiac catheterization.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AZ Sint Jan
Bruges, Belgium
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Jessa Ziekenhuis
Hasselt, Belgium
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LKH Hochsteiermark, Standort Bruck
Bruck an der Mur, Austria
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LKH II Standort West
Graz, 8020, Austria
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Medical University of Graz
Graz, Austria
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OLV Aalst
Aalst, Belgium
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San Pietro Hospital
Rome, Italy
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Sant´Andrea Hospital
Rome, Italy
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University Hospital D'Annunzio Chieti
Chieti, Italy
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