AI reads your gut scans to spot disease without a scope
NCT ID NCT07087418
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is developing an artificial intelligence system that analyzes CT and MRI scans to diagnose and predict outcomes for digestive diseases like Crohn's disease, ulcerative colitis, and intestinal tuberculosis. Researchers are using data from 21 hospitals in China to train the AI, and will test it in two additional hospitals. The goal is to create a noninvasive tool that could reduce the need for colonoscopies and help doctors make faster, more accurate decisions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI diagnostic model using CT and MR imaging
- What this could lead to
- If successful, this could provide a noninvasive way to diagnose and predict the course of digestive diseases, potentially reducing the need for colonoscopies.
- What could go wrong
- This is an observational study, not a treatment trial. The AI model may not perform as well in real-world settings or in different populations, and it is still being tested for accuracy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This retrospective and prospective study included patients with digestive diseases. For the retrospective component, the investigators enrolled patients from 21 hospitals across China, including the First Affiliated Hospital of Sun Yat-sen University. For the prospective component, the investigators enrolled patients from the First Affiliated Hospital of Sun Yat-sen University and the Third Affiliated Hospital of Guangzhou Medical University.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with multimodal-confirmed diagnoses (clinical, imaging, endoscopic, and pathological) of: * Inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis) * Intestinal tuberculosis * Behçet's disease * Availability of ≥1 technically adequate CT or MR scan with high-quality colonoscopy performed within ±1 month of imaging. Exclusion Criteria: * ・Suboptimal imaging quality (e.g., low-dose artifacts, metal artifacts) * Inadequate bowel preparation for endoscopy * Incomplete examinations due to poor tolerance
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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XploreMET v3.0 system
RECRUITINGShanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Mini-Guts in a dish: scientists probe why IBD tissue struggles to heal
- Can immune aging blood tests predict which older IBD patients thrive on advanced therapies?
- Ulcerative colitis drugs put under the microscope for hidden clot risk
- AI second pair of eyes could speed up finding hidden bleeding
- Can a cheap Anti-Inflammatory drug calm ulcerative colitis?
- Can a liquid diet calm Crohn's in kids?