AI takes on heart failure: could it cut hospital stays?
NCT ID NCT07380555
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an artificial intelligence (AI) system can help doctors manage medications for people with heart failure with reduced ejection fraction (HFrEF). About 1,200 participants from 60 hospitals will be assigned to either AI-guided care or standard care. The goal is to see if AI reduces hospitalizations and heart-related deaths over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- artificial intelligence decision support system
- What this could lead to
- If successful, this could show that AI helps doctors choose better medications for heart failure, potentially reducing hospital stays and saving lives.
- What could go wrong
- This is a large but early-stage study without results yet. The AI recommendations may not improve outcomes over standard care, and the system's accuracy depends on data quality.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,200 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥18 years old; 2. Patients diagnosed with HF in hospital and discharged on medical orders; 3. LVEF≤40% detected by echocardiography within 1 month before enrollment; 4. Signed informed consent is obtained. Exclusion Criteria: 1. Patients who are unable or unsuitable for follow-up. 2. Patients with poor compliance, presenting a risk of switching study groups.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Heart failure with reduced ejection fraction (HF-ref) are added.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shanghai Zhongshan Hospital
Shanghai, Shanghai Municipality, 200032, China