AI tool aims to improve how we measure depression and anxiety
NCT ID NCT07279038
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks if an AI software can accurately measure depression and anxiety symptoms in 650 adults. Participants will have their symptoms rated by both the AI and human experts to see if the AI works well across different groups. The study does not provide any treatment—it only tests the measurement tool.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 650 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2027
An estimate. Start dates often move.
- Expected to finish
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Aug 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
patients with MDD or MDE
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * English fluency * 18 to 65 years of age. * Diagnosed with MDD or MDE (Includes Remission, HAM-D \<= 7) * Starting, or has started, a new treatment for depression or anxiety within 2-3 weeks of enrollment * Access to a laptop or other computer with a well functioning microphone and webcam, and a stable Internet connection * Stated willingness to comply with all study procedures and availability for the duration of the study * Resides in the United States at the time of consent and during completion of study Exclusion Criteria: * Any cognitive impairment that limits ability to provide informed consent or authorization * Vulnerable or protected populations (e.g. prisoners) * Impairment that would prevent participants from completing an online survey and/or engaging in clinician assessment interviews (e.g., visual impairment, motor impairment, hearing impairment) * Acute intoxication at the time of the assessments * Concurrent medication/treatment: * Receiving any fast-acting treatment for depression or anxiety (e.g. ketamine, psychedelics, deep brain stimulation, etc.) in between initial baseline assessment (A1) and Restest (A2) , or in between Follow up assessment (B1) and Retest (B2) * Anxiolytics: Use of benzodiazepines or other anxiety-reducing medications that could affect speech or motor activity, within the past 4 weeks. * Antipsychotics and Mood Stabilizers: Medications that can alter cognitive and motor functions, within the past 6 weeks. * Stimulants: Use of medications like methylphenidate or amphetamines that affect energy levels and behavior, within the past 2 weeks * Epilepsy medication: seizure activity or medication side effects that may alter behavior, within the past 4 weeks. * Any history or evidence of any of the following conditions: * Neurodevelopmental, Neurocognitive, Neurodegenerative or movement disorders including, but not limited to: * Tourette's syndrome * Multiple Sclerosis * Amyotrophic Lateral Sclerosis * Parkinson's Disease * Stroke * Traumatic Brain Injury * Facial paralysis. * Conditions with vocal cord impact: * Vocal cord injury or cerebrovascular accident or head trauma with residual dysarthria in the past year * Disorders that may impact vocal cords such as acute or chronic laryngitis, vocal cord paresis or paralysis, or spasmodic dysphonia * Past or active heavy smokers (an average of \>20 cigarettes per day) * Schizophrenia Spectrum and Other Psychotic Disorders: * Individuals with a current or past diagnosis of Schizophrenia, Schizoaffective Disorder, or other psychotic disorders, including Delusional Disorder and Brief Psychotic Disorder. * Current hypomanic episode as defined by DSM-5 criteria. This includes those with Bipolar I Disorder, Bipolar II Disorder, or Cyclothymic Disorder who are not in a stable mood state at the time of assessment. * Chronic Pain Conditions: Such as fibromyalgia, which may affect facial expressions and vocal tone. * Prosthetic Facial Devices: Could affect facial recognition algorithms. Cosmetic Procedures: Such as Botox injections or facelifts that can impact facial expressions. * Dental Work: Major procedures that might affect speech. * Participants who have previously participated in another research project by Deliberate.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.
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