AI joins the fight against lung cancer: can software spot tumors better?
NCT ID NCT07280559
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether artificial intelligence (AI) software can help radiologists find lung cancer on low-dose CT scans more accurately. About 1,120 adults at risk for lung cancer will be randomly assigned to have their scans read with or without AI assistance. The goal is to see if AI improves cancer detection rates and reduces false alarms, which could lead to better screening outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-assisted low-dose CT interpretation software
- What this could lead to
- If successful, this could make lung cancer screening more accurate and efficient, potentially catching more cancers early and reducing unnecessary follow-ups.
- What could go wrong
- This is an early-stage study that hasn't started recruiting yet. The AI may not improve accuracy enough to change practice, and results may not apply to all populations or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2031
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 74 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Family History of Lung Cancer: Males aged 45-74 or females aged 40-74 with first-degree relatives (parents, siblings, or children) diagnosed with lung cancer. 2. Heavy Smoking History: Ages 50-74 with ≥20 pack-years smoking history, currently smoking or quit \<15 years ago. 3. General Screening Participants: Adults aged 40 years or older attending routine health check-ups. Exclusion Criteria: 1. Pregnant women. 2. Chest CT or other higher-radiation chest imaging within the past 12 months. 3. Individuals holding a major illness certificate for lung cancer. 4. Inability to undergo thoracic puncture or surgery. 5. Inability to hold breath or otherwise complete the scanning procedure. 6. Hemoptysis of unknown cause within the past month. 7. Chest X-ray within the past month showing suspicious lung lesions. 8. Unexplained weight loss \>6 kg within the past year. 9. History of lung cancer within the past three years. 10. Presence of other severe diseases with an expected life expectancy \<5 years.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Taipei Veterans General Hospital
Taipei, Taiwan, 112, Taiwan
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