Could a low-dose epilepsy drug protect aging brains from dementia?
NCT ID NCT06919926
First seen Apr 17, 2026 · Last updated May 01, 2026 · Updated 3 times
Summary
This study tests whether a low-dose, slow-release form of levetiracetam (AGB101) can reduce overactivity in a key memory region of the brain in healthy older adults. Overactivity in this area is linked to higher dementia risk. Sixty participants aged 50-80 will receive both the drug and a placebo in random order, each for two weeks, and brain scans will measure changes. The goal is to see if the drug safely calms this brain activity, potentially paving the way for future dementia prevention.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Johns Hopkins University School of Medicine
RECRUITINGBaltimore, Maryland, 21287, United States
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